Prenatal paracetamol linked with smaller infant ovaries and testes
Researchers recruited 685 pregnant women in Denmark and tracked medicine use, examining 302 infant girls around three months old and finding that fetal paracetamol exposure was associated with, on average, 40% smaller ovarian volume, 13% smaller uterine volume and 23% fewer ovarian follicles; boys in the cohort also showed reduced testicular volume. A separate analysis of 1,210 Copenhagen girls born 1997–2002 found a similar link in adolescence. The authors and other experts stress the results are associative not proven causal, note possible confounding or chance, and call for long-term follow-up and careful clinical discussion of paracetamol use in pregnancy.
Fetal paracetamol exposure associated with smaller infant reproductive organs.
Context
Researchers asked 685 women about medicine use every two weeks and did fetal and infant exams. The findings showed dose-related associations and a separate adolescent dataset supported smaller ovaries. Next steps could include longer…
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