COVID-19 immunity protects against some bat coronaviruses
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Scientists at the Pirbright Institute and King's College London report in two companion PLOS Biology articles that immunity from SARS-CoV-2 infection or vaccination can cross-neutralize a range of bat sarbecoviruses. The team tested 15 representative bat coronavirus spike proteins against ACE2 receptors from 34 species and found generalist viruses concentrated in the SARS-CoV-2 lineage. Blood from recovered COVID-19 cases neutralized several closely related bat viruses, and monoclonal antibodies were found that bind conserved spike regions. The findings suggest existing immunity may partially protect humans and guide pan-sarbecovirus vaccine and surveillance strategies.
SARS-CoV-2 immunity partly neutralizes related bat sarbecoviruses
Context
Researchers studied sarbecoviruses after the COVID-19 pandemic. They tested spike…
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